Medical research

  1. Flail chest stabilization with Palacos prosthesis The approach and management of patients with post-traumatic flail chest continue to be a controversial issue. A method of surgical stabilization of flail chest using palacos, a cement-like material is described. A ready-made prosthesis is placed on the external side of the ribs vertically bridging the flailed chest segment, and fixed to the first upper and first lower intact rib as well as to the mobile segments of the affected ribs. Surgical fixation was carried out in 56 patients. The results proved the method to be a simple and effective procedure.
  2. Experimental and clinical study in the treatment of sigmoid volvulus It is the method for surgical treatment sigmoid volvulus colon, while not yet irreversible ischemic changes occurred in the intestine and are carried out by the principle of sigmoidoscopy without resection procedures. Method is simple to perform, efficient and low risk.
  3. Pancreatic resection and hipotermic peritoneal irrigation in the treatment of patients with necrotizing pancreatitis Untill 1973, the patients with necrotizing pancreatitis were treated with conservative methods. That year, the first pancreatic resection had been performed due to necrotizing process, and next year, another one. As a witness to dying patients with progressive massive necrotizing pancreatitis, he starts to develop a strategy for surgical treatment of these patients on the basis of previous medical knowledge. In 1976 he starts to perform this integral method, which basically consists in resection of pancreatic necrosis with the removal of necrotic tissue peripancreatic (if any) and applying a high degree of regional hypothermia on selected patients in whom disease progression is unstoppable in spite of intensive conservative therapy. This method has successfully cured 74% of patients in the first series of 49 treated individuals, and we are confident that this method can reduce postoperative mortality and under 20%. The method consists of regional hypothermia irrigation particular region, or focus the process with Ringer solution temperature plus four levels, which contributes to the normalization of regional and general hemodynamics, stunted growth and reproduction of microorganisms, increases the sensitivity of microflora to antibiotics, and reduces the absorption of bacterial toxins in the blood. The method of hypothermia can be applied to other severe inflammatory processes: pleural empyema with or without bronhopleuralne fistula, for pleural empyema as complications after lobectomy or pulmectomy especially when it comes to causative factors such highly resistant strains to antibiotics, but also in severe forms of diffuse peritonitis, purulent arthritis and others with significantly better results and faster healing than if the treatment is performed without regional hypothermia.
  4. New performance techniques of terminolateral anastomosis and remote results Anastomosis is performed in an original way so that almost perfect mimic natural branching blood vessels without stenosis and dilation at the junction, which gives it a distinct advantage from a hemodynamic point of view in comparison with other methods which contributes to the duration of patency of anastomosis including graft. That has been confirmed with physical and mathematical calculations by testing the flow model compared with other methods and finally, applying in 112 treated patients in whom this method derived aortofemoral bypass graft with a five-year survival of 94.3% and with ten-year graft survival of 91.1%. These results support the value of this method.
  5. Smaller contributions on perfecting surgical techniques Surely, there are the so-called cross sutures which are applied in performing intestine-pancreatic anastomosis especially when performing cephalic pancreaticoduodenectomy which provides greater strength of sutures and less chance of anastomotic dehiscence; here I think it is worth to mention oblique suture in creating esophageal intestinal anastomosis which brings us to the anatomy of the esophagus membrane, which also gives more strength and less likely failure of anastomosis. It is also worth to mention performing of abdominoperineal amputation with preservation of anal sphincter by Bacon, but without creating preternatural anus etc.
  6. He is the first in the world performed subclavian femoral bypass on the veins with superior vena cava syndrome due to progressive fibrosing mediastinitis
  7. He is the first in the world who, because of agenesis, successfully replaced the right hemidiaphragm with alloplastic mesh on adult person.
  8. Performed the first completely successful implantation of the hand in the upper arm in Yugoslavia.
  9. Performed first and then a series of 21 operations sliding hiatal hernia, according to Hill’s method, in Yugoslavia, certainly the best method to treat these disease
  10. He first began with the serial of surgical procedures for treating extreme obesity in Yugoslavia
  11. In a young patient with deceleration rupture in the first segment of the descending aorta which was simply cut transversely across the circumference, remained intact only in the width of 1 inch of membrane blood vessels. Aorta was reconstructed fast enough that patients are not any other consequences nor even neurological consequences (which is not a small rarity).
  12. Patented device for electronic control of aseptic prevention with sound and light indicators.
  13. Patented portable or pocket-sized device for electronic control of aseptic prevention with sound and light indicators. Both devices are primarily intended to promptly detect cracking of surgical gloves while performing surgical operations.
  14. Patented device for early detection of brain energy crisis occurs.
  15. At the International Fair of Innovations he won one gold and five silver medals.